{"id":12494,"date":"2021-12-21T09:44:15","date_gmt":"2021-12-21T08:44:15","guid":{"rendered":"https:\/\/blog.wika.com\/en\/?p=12494"},"modified":"2023-02-02T13:08:28","modified_gmt":"2023-02-02T12:08:28","slug":"unique-diaphragm-pressure-gauge-for-pharmaceutical-industry","status":"publish","type":"post","link":"https:\/\/blog.wika.com\/en\/applications\/unique-diaphragm-pressure-gauge-for-pharmaceutical-industry\/","title":{"rendered":"Unique: Diaphragm pressure gauge for pharmaceutical industry"},"content":{"rendered":"<p><strong>Requirement and solution \u2212 The following example from China shows WIKA&#8217;s competence in the pharmaceutical sector: One of the biggest vaccine manufacturers in China urgently needed a safe and autoclavable pressure gauge in hygienic design for the production of an anti-Covid vaccine. Its task: Monitoring pressure before and after filtration where the finished vaccine is purified. The solution: PG43SA series diaphragm pressure gauges from WIKA.<\/strong><\/p>\n<p>In the course of production, the filter system is sterilised at regular intervals in autoclaves, under saturated steam conditions at 121 \u00b0C, complete with the fitted measuring instruments. The <a href=\"https:\/\/www.wika.com\/en-en\/lp_pressure_gauge.WIKA\" rel=\"external\" target=\"_blank\">pressure gauge<\/a> has to cope with this process. In view of the urgent demand for vaccines, the manufacturer had to procure the required number of measuring instruments as rapidly as possible in order to ramp up production.<\/p>\n<h2>Diaphragm pressure gauges offer numerous benefits for the pharmaceutical industry<\/h2>\n<p>As a solution, the pharmaceutical experts from WIKA China offered the PG43SA series diaphragm pressure gauges. WIKA designed these measuring instruments specifically for the requirements of sanitary applications. Due to their purely mechanical pressure transmission (thus needing no external power) and also their high overload safety, they guarantee continuous and safe pressure measurement. These pressure gauges operate with a dry measuring cell and this eliminates the risk of contamination of the product by any transmission fluid.<\/p>\n<p>All PG43SA instruments can also be autoclaved in a reliable cleaning process. The hygienic pressure gauge series thus satisfied the general requirements of the vaccine manufacturer, who also already uses other WIKA measuring instruments. Above all, the company focused on the PG43SA-C model. The selected design is also incredibly compact, which ultimately also tipped the scales in favour of the customer ordering. Furthermore, an integrated process connection enables space-saving installation. There is currently no comparable instrument on the market \u2212 the diaphragm pressure gauge in the selected design is therefore unique and ideally suited for use in the pharmaceutical industry.<\/p>\n<p><strong>Note<\/strong><br \/>\nFurther information on the <a href=\"https:\/\/www.wika.com\/en-en\/pharmaceuticals_and_biotechnology.WIKA\" rel=\"external\" target=\"_blank\">pharmaceutical and biotechnology<\/a> industries and also on <a href=\"https:\/\/www.wika.com\/en-en\/pressure.WIKA\" rel=\"external\" target=\"_blank\">pressure measurement<\/a> can be found on the WIKA website. Details on the different versions of the diaphragm pressure gauge series can be found on the respective product pages: <a href=\"https:\/\/www.wika.com\/en-en\/pg43sa_c.WIKA\" rel=\"external\" target=\"_blank\">PG43SA-C<\/a>, <a href=\"https:\/\/www.wika.com\/en-en\/pg43sa_d.WIKA\" rel=\"external\" target=\"_blank\">PG43SA-D<\/a>, <a href=\"https:\/\/www.wika.com\/en-en\/pg43sa_s.WIKA\" rel=\"external\" target=\"_blank\">PG43SA-S<\/a>. You would like to buy the diaphragm pressure gauge PG43SA-S? In our <a href=\"https:\/\/shop.wika.com\/en-en\/pg43sa_s.WIKA\" rel=\"external\" target=\"_blank\">WIKA online-shop<\/a> you will find some of our standard designs. If you have any questions, please do not hesitate to <a href=\"https:\/\/www.wika.com\/en-en\/contact.WIKA\" rel=\"external\" target=\"_blank\">contact<\/a> us.<\/p>\n<p><strong>Watch the following video to find out more about safe pressure measurement in sanitary applications \u2212 Diaphragm pressure gauges in hygienic design:<\/strong><\/p>\n<div data-fullscreen=\"disabled\" data-mode=\"normal\" data-oembed=\"1\" data-provider=\"youtube\" data-reset-after-played id=\"arve-youtube-dha4xrdjp88\" style=\"max-width:900px;\" class=\"arve\">\n<div class=\"arve-inner\">\n<div style=\"aspect-ratio:500\/281\" class=\"arve-embed arve-embed--has-aspect-ratio\">\n<div class=\"arve-ar\" style=\"padding-top:56.200000%\"><\/div>\n<p>\t\t\t<iframe allow=\"accelerometer &apos;none&apos;;autoplay &apos;none&apos;;bluetooth &apos;none&apos;;browsing-topics &apos;none&apos;;camera &apos;none&apos;;clipboard-read &apos;none&apos;;clipboard-write;display-capture &apos;none&apos;;encrypted-media &apos;none&apos;;gamepad &apos;none&apos;;geolocation &apos;none&apos;;gyroscope &apos;none&apos;;hid &apos;none&apos;;identity-credentials-get &apos;none&apos;;idle-detection &apos;none&apos;;keyboard-map &apos;none&apos;;local-fonts;magnetometer &apos;none&apos;;microphone &apos;none&apos;;midi &apos;none&apos;;otp-credentials &apos;none&apos;;payment &apos;none&apos;;picture-in-picture;publickey-credentials-create &apos;none&apos;;publickey-credentials-get &apos;none&apos;;screen-wake-lock &apos;none&apos;;serial &apos;none&apos;;summarizer &apos;none&apos;;sync-xhr;usb &apos;none&apos;;web-share;window-management &apos;none&apos;;xr-spatial-tracking &apos;none&apos;;\" allowfullscreen=\"\" class=\"arve-iframe fitvidsignore\" credentialless data-arve=\"arve-youtube-dha4xrdjp88\" data-lenis-prevent=\"\" data-src-no-ap=\"https:\/\/www.youtube-nocookie.com\/embed\/dhA4XRDjP88?feature=oembed&amp;iv_load_policy=3&amp;modestbranding=1&amp;rel=0&amp;autohide=1&amp;playsinline=0&amp;autoplay=0&amp;enablejsapi=1\" frameborder=\"0\" height=\"505.8\" loading=\"lazy\" name=\"\" referrerpolicy=\"strict-origin-when-cross-origin\" sandbox=\"allow-scripts allow-same-origin allow-presentation allow-popups allow-popups-to-escape-sandbox\" scrolling=\"no\" src=\"https:\/\/www.youtube-nocookie.com\/embed\/dhA4XRDjP88?feature=oembed&#038;iv_load_policy=3&#038;modestbranding=1&#038;rel=0&#038;autohide=1&#038;playsinline=0&#038;autoplay=0&#038;enablejsapi=1\" title=\"Safe pressure measurement in sanitary applications | Diaphragm pressure gauges in hygienic design\" width=\"900\"><\/iframe><\/p><\/div>\n<\/p><\/div>\n<p>\t<script type=\"application\/ld+json\">{\"@context\":\"http:\\\/\\\/schema.org\\\/\",\"@id\":\"https:\\\/\\\/blog.wika.com\\\/en\\\/applications\\\/unique-diaphragm-pressure-gauge-for-pharmaceutical-industry\\\/#arve-youtube-dha4xrdjp88\",\"type\":\"VideoObject\",\"embedURL\":\"https:\\\/\\\/www.youtube-nocookie.com\\\/embed\\\/dhA4XRDjP88?feature=oembed&iv_load_policy=3&modestbranding=1&rel=0&autohide=1&playsinline=0&autoplay=0&enablejsapi=1\",\"name\":\"Safe pressure measurement in sanitary applications | Diaphragm pressure gauges in hygienic design\",\"thumbnailUrl\":\"https:\\\/\\\/i.ytimg.com\\\/vi\\\/dhA4XRDjP88\\\/hqdefault.jpg\",\"uploadDate\":\"2019-04-11T13:19:09Z\",\"author\":\"WIKA Group\",\"description\":\"Diaphragm pressure gauge and their role in the production of food and pharmaceuticals. The highest priority in those areas is safety. In sanitary applications, such as, for example, in the production of vaccines or baby food, the purity, quality, and stability of the product must be ensured.\\nIn pipelines, fermenters, bioreactors, or vessels, the pressure needs to be indicated via easy-to-read pressure gauges. Pressures and vacuums must be monitored constantly during cleaning (CIP\\\/SIP), sterilisation and testing.\\nThe process reliability can be guaranteed through measuring instruments in hygienic design. In the following, we will introduce you to the most important instruments, the process risks, and innovative solutions.\\n\\n#FoodSafety #Pharma #WIKAgroup #Pharmaceuticals #Sanitary #SterileProcessing #FoodIndustry\\n\\n\\u25ac Chapters of the video \\u25ac\\u25ac\\u25ac\\u25ac\\u25ac\\u25ac\\u25ac\\u25ac\\u25ac\\u25ac\\n00:00 - Introduction\\n00:36 - Diaphragm seal systems\\n01:37 - Diaphragm pressure gauges\\n02:08 - Special diaphragm pressure gauges by WIKA\\n2:38 - PG43SA-S diaphragm pressure gauge for mobile tanks\\n2:55 - PG43SA-C diaphragm pressure gauge for limited spaces\\n3:11 - PG43SA-D diaphragm pressure gauge for stringent safety requirements\\n\\nDiaphragm seal systems have long proven themselves as a standard. The diaphragm of the diaphragm seal transmits the pressure to the sensor element of the pressure gauge (video:  Mechanical and electronic pressure measuring instruments can be combined with diaphragm seals to adapt the instrument for high temperatures, aggressive media or for easy cleanability.\\nThrough carelessness such as rough handling, but also as a result of pressure spikes and overload, the sensitive diaphragm of the diaphragm seal can be damaged. If the diaphragm rupture is not detected in time or even if the transmission fluid flows into the process, this involves process risks. The consequences could cause great economic damage and even be fatal: contamination of medicines, destruction of entire batches or suspension of production.\\nWith special WIKA pressure measuring instruments, a diaphragm rupture can be detected immediately. Diaphragm seal systems with built-in diaphragm monitoring or diaphragm pressure gauges can reliably monitor such processes.\\nDiaphragm pressure gauges: Here, the pressure is transmitted mechanically to the movement \\u2212 this is done without any transmission fluid and thereby increases the process reliability (video:  Because the diaphragm element is very robust, it is resilient to extreme process conditions as well as rough handling. Thus, diaphragm pressure gauges eliminate a large number of process risks in sanitary applications and increase the plant availability and the service life of the measuring instrument.\\n\\nThe solution: PG43SA series diaphragm pressure gauges are designed to meet the highest demands of the food and pharmaceutical industries. These pressure gauges fulfil the strict requirements of hygienic design and this is confirmed through 3-A and EHEDG certificates. Bioreactors, fermenters or buffer tanks can be autoclaved directly along with the measuring instruments. Dismounting them is not necessary, saving valuable time.\\n\\nPG43SA-S diaphragm pressure gauge ( The pressure in mobile and high vessels, fermenters or bioreactors can be read off using the PG43SA-S diaphragm pressure gauge. It features a large display. Due to the radial connection, this model is also particularly well suited for connection to horizontal pipelines.\\n\\nPG43SA-C diaphragm pressure gauge ( The compact PG43SA-C diaphragm pressure gauge with its patented design is ideal for mounting on vertical pipelines or small mobile vessels. The process connection is located at the rear of the case and enables space-saving installation. \\n\\nPG43SA-D diaphragm pressure gauge ( The high-end model PG43SA-D version meets the highest safety requirements and can completely eliminate the risk of undiscovered diaphragm element ruptures. This is ensured through the integrated diaphragm element monitoring. Via an additional indication on the dial, the integrity of the diaphragm element can be checked with just one glance, not only before installation, but also during operation. A second barrier enables double security and guarantees that media cannot enter into the process or the environment. The process is therefore hermetically sealed in the event of a diaphragm element rupture. If the monitoring function is required for pressure measuring instruments with an electrical output signal, the diaphragm monitoring system with diaphragm seal ( is available for this purpose.\\n\\nBlog posts on the subject: \\n\\n\\u25ac Follow us \\u25ac\\u25ac\\u25ac\\u25ac\\u25ac\\u25ac\\u25ac\\u25ac\\u25ac\\u25ac\\u25ac\\u25ac\\n\\ud83d\\udcfa YouTube: \\n\\u2705 LinkedIn:\"}<\/script><\/p>\n<\/div>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Requirement and solution \u2212 The following example from China shows WIKA&#8217;s competence in the pharmaceutical sector: One of the biggest vaccine manufacturers in China urgently needed a safe and autoclavable pressure gauge in hygienic design for the production of an anti-Covid vaccine. Its task: Monitoring pressure before and after filtration where the finished vaccine is [&hellip;]<\/p>\n","protected":false},"author":134,"featured_media":12495,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[232],"tags":[714,75,575],"class_list":["post-12494","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-applications","tag-pharmaceuticals-and-biotechnology","tag-pressure-gauge","tag-pressure-measurement-device"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Unique: Diaphragm pressure gauge for pharmaceutical industry - WIKA blog<\/title>\n<meta name=\"description\" content=\"Requirement and solution \u2212 WIKA convinces with diaphragm pressure gauges in the pharmaceutical industry. 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